MyBioSource.com's CD15/ Lewis X antigen/ alpha-(1,3)-fucosyltransferase 4 is a Mouse monoclonal antibody. The CD15/ Lewis X antigen/ alpha-(1,3)-fucosyltransferase 4 Antibody was generated using CD15, FUT4, Lewis X, and Lex as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
CD15 is a carbohydrate that is referred to as the Lewis X antigen, also known as alpha-(1,3)-fucosyltransferase 4, which is expressed on a variety of glycolipids and glycoproteins found on the cell surface of neutrophils, monocytes, eosinophils and non-hematopoietic tissues including embryonic tissues. CD15 is reported to function as an adhesion molecule and is involved in chemotaxis and phagocytosis. Expression of CD15 is also associated with a wide variety of tumour cells including some adenocarcinomas and certain types of myeloid and lymphoid leukaemias. Reed-Sternberg cells, found in cases of Hodgkins Lymphoma, also express CD15 and antibodies recognising the CD15 antigen are often used to help differentiate between Hodgkins and non-Hodgkins lymphoma